Watch this space for updates on MS SPIDOC-related scientific publications.

Charge Engineering Reveals the Roles of Ionizable Side Chains in Electrospray Ionization Mass Spectrometry. Mia L. Abramsson, Cagla Sahin, Jonathan T. S. Hopper, Rui M. M. Branca, Jens Danielsson, Mingming Xu, Shane A. Chandler, Nicklas Österlund, Leopold L. Ilag, Axel Leppert, Joana Costeira-Paulo, Lisa Lang, Kaare Teilum, Arthur Laganowsky, Justin L. P. Benesch, Mikael Oliveberg, Carol V. Robinson, Erik G. Marklund, Timothy M. Allison, Jakob R. Winther and Michael Landreh. JACS Au 2021, DOI: 10.1021/jacsau.1c00458

Protein orientation in time-dependent electric fields: orientation before destruction. Anna Sinelnikova, Thomas Mandl, Harald Agelii, Oscar Grånäs, Erik G. Marklund, Carl Caleman and Emiliano De Santis. Biophysical Journal 2021 (120)17, DOI: 10.1016/j.bpj.2021.07.017

In a flash of light: X-ray free electron lasers meet native mass spectrometry. Alan Kadek, Kristina Lorenzen, Charlotte Uetrecht for MS SPIDOC consortium.
Drug Discovery Today: Technology 2021 08,
DOI: 10.1016/j.ddtec.2021.07.001

A comic-book take on a virus photoshoot

‘Norovirus Superstar’ gives insights into the EU-funded MS SPIDOC project and explains how European XFEL is used in biology.

© 2021 Véro Mischitz | MS SPIDOC, CC BY ND 4.0 doi:10.22003/XFEL.EU-COMIC-2021-001-EN

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Reproducibility in the unfolding process of protein induced by an external electric field. Anna Sinelnikova, Thomas Mandl, Christofer Östlin, Oscar Grånäs, Maxim N. Brodmerkel, Erik G. Marklund and Carl Caleman
Chemical Science 202112, 2030-2038
DOI: 10.1039/D0SC06008A

Structural Heterogeneity in Single Particle Imaging Using X-ray Lasers. Thomas Mandl, Christofer Östlin, Ibrahim E. Dawod, Maxim N. Brodmerkel, Erik G. Marklund, Andrew V. Martin, Nicusor Timneanu, and Carl Caleman
The Journal of Physical Chemistry Letters2020 11 (15), 6077-6083
DOI: 10.1021/acs.jpclett.0c01144

Glycan-Induced Protein Dynamics in Human Norovirus P Dimers Depend on Virus Strain and Deamidation Status. Jasmin Dülfer, Hao Yan, Maxim N. Brodmerkel, Robert Creutznacher, Alvaro Mallagaray, Thomas Peters, Carl Caleman, Erik G. Marklund and Charlotte Uetrecht. Molecules 2021 26(8), 2125. doi: 10.3390/molecules26082125

The XBI BioLab for life science experiments at the European XFEL. Huijong Han, Ekatarina Round, Robin Schubert, Yasmin Gül, Jana Makroczyová, Domingo Meza, Philipp Heuser, Martin Aepfelbacher, Imrich Barák, Christian Betzel, Petra Fromme, Inari Kursula,  Poul Nissen,  Elena Tereschenko, Joachim Schulz, Charlotte Uetrecht, Jozef Ulicný, Matthias Wilmanns, Janos Hajdu,  Victor S. Lamzin and Kristina Lorenzen. Journal of Applied Chrystallography 2021 54(1). doi: 10.1107/S1600576720013989

Characterization of native protein structure with ion mobility mass spectrometry, multiplexed fragmentation strategies and multivariant analysis. Rachelle Black, Alexey Barkhanskiy, Lennart A. I. Ramakers, Alina Theisen, Jeffery M. Brown, Bruno Bellina, Drupad Trivedi and Perdita E. Barran. International Journal of Mass Spectroscopy 2021 464 (116588). doi: 10.1016/j.ijms.2021.116588

Interplay between chromophore binding and domain assembly by the B12-dependent photoreceptor protein, CarH. Inês S. Camacho, Rachelle Black, Derren J. Heyes; Linus O. Johannissen, Lennart A.I. Ramakers, Bruno Bellina, Perdita E. Barran, Sam Hay, and Alex R. Jones. Chemical Science 2021 24. doi: 10.1039/D1SC00522G

Chapter 10: Photoactivation and Dissociation in Biomolecular Mass Spectrometry. Rachelle Black, Perdita E. Barran and Lennart A. I. Ramakers. In: Advanced Fragmentation Methods in Biomolecular Mass Spectrometry: Probing Primary and Higher Order Structure with Electrons, Photons and Surfaces. Frederik Lermyte (ed.) 2020. doi: 10.1039/9781839161056-00235